TOXICOLOGIC STUDIES WITH YTTRIUM NITRATE AND LANTHANUM NITRATE AS MODIFIED BY SITE OF INJECTION AND WHOLE-BODY RADIATION
Technical Report
·
OSTI ID:4296715
ABS> Yttrium snd lanthanum, in the nitrate form, were administered by various avenues to rats, some of which had been subjected to whole-body irradiation by Co/sup 60/ gamma rays. Rats receiving intraperitoneal injections of yttrinm nitrate plus whole-body exposure to ionizing rndiation evidenced a higher mortality (significant to the 5 percent confidence level) than rats receiving either radiation or intraperitoneal injections of yttrinm nitrate alone. Subcutaneous injection of 200 mg of yttrium or lanthamum nitrate caused abscess formation and subsequent epilation. No effect was noted when sodium nitrate or saline were similarly injected into rats. The presence of yttrium and lanthanum nitrates caused delayed healing of wounds. Similar effects were not produced when sodium nitrate was administered in the same manner. (auth)
- Research Organization:
- School of Aviation Medicine, Randolph AFB, Tex.
- NSA Number:
- NSA-12-016914
- OSTI ID:
- 4296715
- Report Number(s):
- AF-SAM-58-88
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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