EFFECTS OF IRRADIATED MEDIA ON THE SPLEEN TISSUE TRANSPLANTATION

Journal Article · Sun Jan 11 04:00:00 EST 1959 · Doklady Akad. Nauk S.S.S.R.

OSTI ID:4289019

Ivanitskaya, A F

The participation and effects of plasma media irradiated with 5000 and 100,000 r gamma rays on cell growth in spleen section transplantation were studied. The medium irradiated with 100,000 r was used the same day, the next, and 2 days later. The results showed that the irradiation of media (extract and plasma) with 100,000 r affects the growth and behavior of nonirradiated mouse spleen, produces toxic effects in the growing culture cells, and induces serious disturbances in the blood cells, especially lymphocytes. The connectiag tissue cells are also badly afflicted. In the medium irradiated with 5000 r the free blood cells undergo pathological changes and are destroyed on the second day following the exposure, while the reticular elements retain their morphological and functional properties and the changes which might take place do not affect general functions of the tissue as a whole. The lymphoid group of the three basic spleen cells (lymphoid. granular and reticular) is the first affected and the last to restore itself. (R.V.J.)

• Research Organization: Severtsov Inst. of Animal Morphology, Academy of Sciences, USSR
• NSA Number: NSA-13-009583
• OSTI ID: 4289019
• Journal Information: Doklady Akad. Nauk S.S.S.R., Journal Name: Doklady Akad. Nauk S.S.S.R. Vol. Vol: 124
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
BLOOD CELLS
BLOOD PLASMA
CONNECTIVE TISSUE
ENVIRONMENT
EXPANSION
GAMMA RADIATION
LYMPH SYSTEM
LYMPHOCYTES
MICE
MITOSIS
RADIATION DOSES
RADIATION EFFECTS
RECOVERY
SPLEEN
TISSUE CULTURES
TISSUES
TOXICITY
TRANSPLANTS