On the Role of Adrenal Glands in the Development of Radiation Diseases; K VOPROSU O ROLI NADPOCHECHNIKOV V PATOGENEZE LUCHEVOI BOLEZNI

Technical Report · Sat Oct 31 04:00:00 EST 1959

OSTI ID:4287758

Tonkikh, A V ^[1]

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1. Tonkih

One of the after effects of x-ray action on the organism is the change in the activity of the cortex of adrenal glands. This change is expressed in its more intensive activity during the first days after irradiation and in a drastic decrease of this activity during the following days. The activity of the cortex of adrenal glands was measured with due account of the efficiency of skeletal muscles. Special experiments have shown that these changes in the cortex of adrenal glands cannot be entirely referred to as the changes in the content of adreno-corticotropic hormon in the organism, ACTH. A possibility of direct reflex influence on the cortex of adrenal glands is not excluded. Previously it was shown that analogous changes in activity also take place in the cerebral layer of adrenal glands. These changes can be revealed from Tonkih-Ilyina phenomenon, i.e., from the presence of the second durable and delayed wave of blood pressure increase which is due to the secretion, under the influence of adrenaline, of vascular hormone by the posterior lobe of the hypophysis. These changes in the activity of adrenal glands may account for some symptoms of railiation disease, e.g., adynamia and hypotonia, caused by participation of cortical hormone and adrenaline in various metabolic reactions. (auth)

• Research Organization: U.S.S.R.
• NSA Number: NSA-13-006289
• OSTI ID: 4287758
• Report Number(s): A/CONF.15/P/2132
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ACTH
ADRENAL GLANDS
ADRENALINE
BIOLOGY AND MEDICINE
BLOOD CIRCULATION
GLANDS
HORMONES
MEASURED VALUES
METABOLISM
MUSCLES
PITUITARY GLAND
PRESSURE
RADIATION EFFECTS
RADIATION SICKNESS
VARIATIONS
X RADIATION