TOTAL EXCHANGEABLE POTASSIUM AND CHLORIDE AND TOTAL BODY WATER IN HEALTHY MEN OF VARYING WATER AND FAT CONTENT
During recent years it has been shown that various parameters and functions of body composition, among them exchangeable potassium, sodium, chloride, total red cell mass, plasma volume, indices of extracellular fluid volume, and creatinine excretion, all are quite closely correlated with the size of the lean body mass. This is true not only in man, but in a variety of lower animals. Recent advances in methods have made it possible to measure exchangeable potassium using mixing times of 40 hours. Also, it has been shown that for sick patients, a mixing time at least this long should be used for purposes of accuracy. Most of the data in the literature for exchangeable potassium in healthy men has been gathered using mixing times of 24 hours. In addition, it has been reported that gains or losses of weight have been associated with alterations in both extracellular fluid and total body water. Because of these factors, measurements of exchangeable potassium, exchangeable chloride, and total body water were performed in a group of 36 healthy men of varying water and fat content. The results showed a marked correlation between the amount of exchangeable potassium or chloride in the body and the amount of water in the body. In addition, it was seen that the amount of exchangeable chloride increased in proportion to the relative amount of fat in the body, and decreased in propotion to the relative amount of water in the body. Fat men contained relatively more chloride per unit of body water than did average men, and average men contained more than did lean men. No such relationship was present for the amount of exchangeable potassium, which was constant, with relation to the body water, over a wide range of water or fat content. (auth)
- Research Organization:
- Naval Radiological Defense Lab., San Francisco
- NSA Number:
- NSA-13-012359
- OSTI ID:
- 4270943
- Report Number(s):
- USNRDL-TR-313
- Resource Relation:
- Other Information: Orig. Receipt Date: 31-DEC-59
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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