Effects of X-Rays on Mercaptobenzothiazole Treated Mice; L'INFLUENCE DES RADIATIONS X SUR LES RATS TRAITES AVEC DU MERCAPTO- BENZO-THIAZOLE (MBT)

Technical Report · Sat Oct 31 04:00:00 EST 1959

OSTI ID:4270916

Pora, A E; Pop, M

The susceptibility and resistance of the central nervous system to ionizing radiations were studied. Foodconditioned reflexes were developed in mice. Once these reflexes were well established, the animals were divided into a control group and a sample group. The sample group received 4 x 10/sup -5/ mole of mercaptobenzothiazole per 20 g of body weight. Both groups were BIOLOGY irradiated with 700 r of x radiatlon. All the controls died within two days, whereas all the mice which had received mercaptobenzothiazole survived. The surviving mice, however, lost all the conditioned reflexes. More than three weeks were required for the reflexes to be restored to their initial value. Although the cerebral cortex is very susceptible to radiation, irradiation does not cause modifications in the anatomical structure of the cortex. Mercaptobenzothiazole confers effective radioprotection, but it does not prevent functional cortical disturbances. (auth)

• Research Organization: Univ. of Cluj
• NSA Number: NSA-13-006168
• OSTI ID: 4270916
• Report Number(s): A/CONF.15/P/1289
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BEHAVIOR
BIOLOGY AND MEDICINE
BRAIN
CONDITIONED REFLEXES
FOOD
GAMMA RADIATION
MICE
ORGANIC SULFUR COMPOUNDS
PHYSIOLOGY
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
RADIATION PROTECTION
RADIOSENSITIVITY
RECOVERY
X RADIATION