STUDY OF RADIOACTIVE PHOSPHORUS (P$sup 32$) DISTRIBUTION IN MAN BY EXTERNAL BREMSSTRAHLUNG MEASUREMENTS

Technical Report · Sat Oct 31 04:00:00 EST 1959

OSTI ID:4265860

Tubiana, M; Albarede, P; Nahum, H

The range in tissues of beta particles emitted by phosphorus-32 is so short that the study of radiophosphorus distribution in a human organism by external counting methods does not seem valid. lt ils for this reason that it seemed useful to establish new techniques based on the detection of Bremsstrahlung. By means of a scintillatilng counter and a singlechamel selector it ils possible to follow in the human body the radioactivity of different viscera, such as the liver and the spleen, and to compare the uptake in a tumor and neighboring or symmetrucal healthy tissues after injecting a dose of not more than 200 microcuries of radiophosphorus. Preliminary studies with a phantom showed that it is possible to obtain a counting rate per microcurie of radiophosphorus equal to 1/20 of that which is obtained by the same dose of iodine under the same geometrical conditions. Under the conditions chosen, the radiation measured has physical charucieristics similar to those of a 120-Kev gamma radiation. The limits and possibilities of using this method on man are discussed as well as the usefulness it can have for diagnosis and prognostic studies. (C.H.)

• Research Organization: Inst. Gustave Roussy, Villejuif, France
• NSA Number: NSA-13-006867
• OSTI ID: 4265860
• Report Number(s): A/CONF.15/P/1222
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BODY
BREMSSTRAHLUNG
DETECTION
DISTRIBUTION
EFFICIENCY
ENERGY
GAMMA RADIATION
INJECTION
LIVER
MAN
MEASURED VALUES
PHOSPHORUS 32
PHYSICS AND MATHEMATICS
PULSE ANALYZERS
RADIOACTIVITY
RADIOISOTOPES
SCINTILLATION COUNTERS
SENSITIVITY
SPLEEN
TISSUES
TUMORS
USES