STUDIES ON RADIATION-INDUCED LEUKEMIA IN MICE

Journal Article · Wed Apr 01 04:00:00 EST 1959 · Cancer Research

OSTI ID:4265366

Gross, L; Roswit, B; Mada, E R; Dreyfuss, Y; Moore, L A

Fractionated total-body x radiation of young adult mice of C3H, C57BR/ cd, A, and I strains induced leukemia in up to 77 per cent of the irradiated mice after a latency varying from 5 to 6 months. Fractionated total-body irradiation of mice of the high-leukemic Ak strain had practically no effect on the incidence of spontaneous leukemia. A group of C3H mice were inoculated when newborn with Ak or C3H leukemia filtrates and then irradiated. The incidence of leukemia in this group was 43 per cent, as compared with 33 per cent in the litter-mate control group which received only the inoculation of the agent. (auth)

• Research Organization: Veterans Administration Hospital, Bronx, N.Y.
• NSA Number: NSA-13-011566
• OSTI ID: 4265366
• Journal Information: Cancer Research, Journal Name: Cancer Research Vol. Vol: 19
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
BODY
CARCINOGENESIS
DOSE FRACTIONATION
LEUKEMIA
MICE
RADIATION DOSES
RADIATION EFFECTS
TRANSPLANTS
X RADIATION