THE EFFECT OF SMALL DOSES OF IONIZING RADIATIONS ON THE DEVELOPMENT OF EXPERIMENTAL LEUKAEMIA IN DOGS

Journal Article · Wed Jan 01 04:00:00 EST 1958 · Problems Hematol. Blood Transfusion (USSR) (English Translation)

OSTI ID:4254155

Lapteva-Popova, M S

Following the daily exposure of dogs to small doses of x rays, a proportion of the animals developed leukaemia from 2.5 to 5 years after the beginning of irradiation. The diagnosis was established on the basis of changes in the peripheral blood and bone marrow. The most significant changes are in the white cell differential count and the myelogram. The number of leucocytes hardly varies. Obvious manifestations of the disease are preceded by delay of cell maturation and a large increase in the more immature forms in the bone marrow; and in the peripheral blood by the presence of immature bone marrow cells and a considerable number of erythroblasts, a rise in the number of basophils and sharp variations in the number of thrombocytes. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-13-007436
• OSTI ID: 4254155
• Journal Information: Problems Hematol. Blood Transfusion (USSR) (English Translation), Journal Name: Problems Hematol. Blood Transfusion (USSR) (English Translation) Vol. Vol: 3
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD CELLS
BONE MARROW
CARCINOGENESIS
DIAGNOSIS
DOGS
LEUCOCYTES
LEUKEMIA
PLATELETS
QUANTITY RATIO
RADIATION INJURIES
VARIATIONS
X RADIATION