PROPHYLACTIC USE OF CERTAIN SULFHYDRYL SUBSTANCES IN EXPERIMENTAL RADIATION AFFECTIONS (in Russian)
Journal Article
·
· Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR
OSTI ID:4239015
In the comparative study of various protective substances, such as salts of beta -mercaptoethylamine, and its derivatives, isothiurone compounds, it has been established that the toxicity of preparations of beta -mercaptoethylamine and beta -aminoethylisothiuronium depends upon the acid part of the compound. The value of the protective effect of these substances is determined by the acid part of the compound, the dosages, the time of introduction, and the length of the observation. These substances lowered the blood pressure by stimulating the parasympathetic innervation. With the substitution of amino-group hydrogens of beta -mercaptoethylamine and beta -aminoethylisothiuronium by methylic and ethylic radicals, the preparations lose their protective properties. beta - mercaptoethylamine, beta -aminoethylisothiuronium, and ethylisothiuronium, when used in effective protective doses, possess a hypothermic and antidiuretic action. There is no parallelism between these properties and the strength of the protective effect of the above agents. (tr-auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-14-001417
- OSTI ID:
- 4239015
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 9; ISSN MERAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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