MORPHOLOGICAL CHANGES OF THE THYROID GLAND IN RATS OF DIFFERENT AGE IN TOTAL X-RAY IRRADIATION

Journal Article · Mon Jun 01 04:00:00 EDT 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4230196

Loskutova, E A

The reaction of the thyroid gland of white male rats to x irradiation (800 r) depends upon the age and individual reactivity of the animal. In young rats the irradiation provokes marked changes in the thyroid gland, which in some instances are expressed by an insignificant rise of the activity (in the first hours and days after irradiation) followed by its decrease (from the 5th to 30th day). In other cases a drop of the activity is seen already in the first hours. In all rats of this group the thyroid gland reverts tu normal towards the second month. In adult rats (5- 7-month-old) the above dose of irradiation provokes less pronounced changes in the structure of the gland, as compared to young rats. Towards the l8th day after irradiation the structure of the thyroid gland normalizes. Irradiation (800 r) of old rats does not cause noticeable changes in the histological picture of the thyroid gland. In young rats with a severe course of radiation sickness, sacrificed in the agonal state on the 9th-l3th day following irradiation, there is a sharp drop of the thyroid gland activity. (auth)

• Research Organization: Pavlov Inst. of Physiology, Academy of Sciences, S.S.S.R.
• NSA Number: NSA-13-016703
• OSTI ID: 4230196
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 6; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

AGE
BIOLOGY AND MEDICINE
CYTOLOGY
PHYSIOLOGY
RADIATION DOSES
RADIATION EFFECTS
RADIATION SICKNESS
RADIOSENSITIVITY
RATS
RECOVERY
SURGERY
THYROID
VARIATIONS
X RADIATION