RELAXATION OF GLYCOGEN CONTENT ALTERATION IN THE LIVER OWING TO IONIZING RADIATION DURING THE IRRADIATION OF ANIMALS IN A CARBON MONOXIDE ATMOSPHERE

Journal Article · Mon Jun 01 04:00:00 EDT 1959 · Doklady Akad. Nauk S.S.S.R.

OSTI ID:4223743

Graevskaya, B M

The effects of carbon monoxide on the alterations in liver tissue glycogen content were studied in animals exposed to lethal doses of irradiation. The experiments were carried out with 195 female and male 8 to 12 weeks old mice weighing 18 to 25 g each. One group was irradiated in a standard atmosphere and the other in an atmosphere containing 0.5 vol. % carbon monoxide. The death rate was 96.9% among the unprotected mice and 24% among the protected mice. The glycogen content in unprotected mice increased during the first 48 hours, after which it steadily dropped, while in the protected animals the glycogen content neither increased or decreased. Consequently, carbon monoxide protection not only increases the rate of survival but also prevents the alteration of glycogen content. (R.V.J.)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-13-017686
• OSTI ID: 4223743
• Journal Information: Doklady Akad. Nauk S.S.S.R., Journal Name: Doklady Akad. Nauk S.S.S.R. Vol. Vol: 126
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

AGE
ATMOSPHERE
BIOLOGY AND MEDICINE
CARBON MONOXIDE
GLYCOGEN
LETHAL DOSE
LIVER
MICE
QUANTITY RATIO
RADIATION EFFECTS
RADIATION PROTECTION
SUGARS
SURVIVAL TIME
TISSUES
VARIATIONS
VOLUME
WEIGHT