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EPIDEMIOLOGICAL STUDIES OF LEUKEMIA IN PERSONS EXPOSED TO IONIZING RADIATION

Journal Article · · Cancer Research
OSTI ID:4211620
After reviewing the epidemiological studies of persons exposed to ionizing radiation, it is concluded that there is no doubt that radiation exposure in man is associated with an increased incidence of leukemia and that a cause-andeffect relationship must be accepted. Such an association holds in the higher dose range regardless of sex and age, the amount of body exposed, and whether or not the radiation was administered as a single dose or intermittently over a long period of time. A proportionality was found to exist between leukemia incidence and dosage in the middle dose range. This relationship was not observed in children treated for thymic enlargement in infancy. Although it has previously been suggested that children are more sensitive to the leukemogenic effects of radiation than adults, it is concluded that the present retrospective studies of prenatal exposure of children dying of leukemia or cancer do not establish exposure to diagnostic doses of radiation as an etiologic factor. (auth)
Research Organization:
Univ. of Rochester, N.Y.
NSA Number:
NSA-14-006139
OSTI ID:
4211620
Journal Information:
Cancer Research, Journal Name: Cancer Research Vol. Vol: 20
Country of Publication:
Country unknown/Code not available
Language:
English

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