SOME MORPHOLOGICAL AND HISTOPATHOLOGICAL CHANGES OCCURRING IN THE CENTRAL NERVOUS SYSTEM OF WHITE RATS IRRADIATED DURING THE ANTENATAL PERIOD (in Russian)
Journal Article
·
· Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR
OSTI ID:4201587
Disturbances of embryogenesis in different structures of the brain (atrophy of the cortex of large hemispheres, corpora callosum, striatum, hippocampus) were observed in the progeny of white rats as remote dates following total irradiation of the gravid animals in the dose of 200 r. Besides edema of the brain and in some cases, even hyctive development of the laminar and the areal structures of the strata, as well as underdevelopment of the V and VI strata of the cortex and large hemispheres in cascs complicated by hydrocephalus is, evidently, connected with the fact that the embryos were irradiated at the period of embryogenesis when the cells of the lower cortical layers were the most sensitive to irradiation. The neuroblasts of the superior layers, which mature later than the inferior ones, are disturbed to a lesser degree. The mechanism of morphological changes in the animals irradiated during the antenatal period of development is associated not only with the direct injurious effect of ionizing radiation on the nerve and glia cells
- Research Organization:
- Inst. of Higher Nervous Activity, Academy of Sciences, USSR
- NSA Number:
- NSA-14-003426
- OSTI ID:
- 4201587
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 11; ISSN MERAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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