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THE INFLUENCE OF NUTRITION ON MUTATION INDUCED BY RADIATION. SIXTH DOUGLAS LEA MEMORIAL LECTURE

Journal Article · · Phys. in Med. Biol.
Evidence is presented which suggests that nucleic acid precursors, arising from purines and pyrimidines and their ribosides, are altered or activated by irradiation. For mutation to occur, these altered precursors must be incorporated into the hereditary nucleic acid and preservation for this incorporation is dependent upon synthe sis of protein immediately following radiation exposure. The altered precursors decay rather rapidly after irradiation unless they are protected by amino acids. The effects of nutritional state and other factors which may also affect nucleic acid synthesis are discussed. (C.H.)
Research Organization:
Univ. of Birmingham, Eng.
NSA Number:
NSA-14-007251
OSTI ID:
4198180
Journal Information:
Phys. in Med. Biol., Journal Name: Phys. in Med. Biol. Vol. Vol: 4
Country of Publication:
Country unknown/Code not available
Language:
English

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