ERYTHROPOIETIC FACTOR IN KIDNEY TISSUE OF ANEMIC DOGS
Journal Article
·
· Proc. Soc. Exptl. Biol. Med.
Homogenates of kidney, liver, and spleen tissue from normal and anemic dogs were assayed for crythropoictic activity by their effect on Fe/sup 59/ red cell incorporation in starved rats. A slightly higher incorporation resulted from adminstration of an extract of anemic kidney than from extract of normal kidney or anemic liver or anemic spleen. This difference was sufficient to suggest the importance of developing methods for concentrating and purifying the erythropoietic activity of tissue homogenates to help clarify the role of kidney in production of erythropoietin. Methods for fractionation and concentration are being investigated. (auth)
- Research Organization:
- Univ. of California, Berkeley
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-007199
- OSTI ID:
- 4188422
- Journal Information:
- Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 103
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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