Metabolic Basis of Calcium and Strontium Discrimination: Studies with Surviving Intestinal Segments
Journal Article
·
· Experimental Biology and Medicine
The differential movement of Ca/sup 45/ and Sr/sup 85/ across surviving intestinal segments of the rat was studied. In the duodenal segment, Ca/sup 45/ but not Sr/sup 85/ was transported against a concentration gradient from mucosa to serosa. In the ileal segment, Sr/sup 85/ but not C a/sup 45/ was transferred against a concentration gradient from serosa to mucosa. Incubation of segments at 0 deg C under N/sub 2/, or in presence of metabolic inhibitors eliminated active transport and eliminated strontium-calcium discrimination. Ca-Sr discrimination under given conditions was dependent upon a metabolically active membrane.
- Research Organization:
- State Univ. Veterinary Coll., Ithaca, N.Y.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-014640
- OSTI ID:
- 4187791
- Journal Information:
- Experimental Biology and Medicine, Journal Name: Experimental Biology and Medicine Journal Issue: 1 Vol. 104; ISSN 1535-3702
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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