THE PARATHYROIDS AND THE INTESTINAL ABSORPTION OF CALCIUM, STRONTIUM AND PHOSPHATE IONS IN THE RAT
The effect of parathyroldectomy (PTX) on the intestinal absorption of calcium, strontium, and phosphate ions was investigated in vivo and in vitro in the rat. At either 5 or 24 hours after parathyroidectomy, the plasma calcium was significantly decreased in comparison to the controls (mock operated) which indicated the success of the operation. It was observed that PTX did not alter the degree of absorption of Ca/sup 45/,Sr/sup 85/, or P/sup 32/ by rat duodenum and ileum in vivo. In rats raised on a high calcium diet, there was an apparent slight decrease in deposition of Ca/sup 45/ and Sr/sup 85/ in the femur; in rats given a low calcium dlet for two weeks, PTX did not influence femur deposition of alkaline earths in respect to the controls. In vitro studies with isolated everted gut segments indicated that the transfer of Ca/sup 45/ and Sr/sup 85/ across the duodenum and ileum was not influenced by the parathyroid status of the donor rat. (auth)
- Research Organization:
- State Univ. Veterinary Coll., Ithaca, N.Y.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-004024
- OSTI ID:
- 4828831
- Journal Information:
- Endocrinology (U.S.), Journal Name: Endocrinology (U.S.) Vol. Vol: 69; ISSN ENDOA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
Transfer of cadmium through the rat's intestinal wall
Discrimination in Intestinal Absorption of Strontium and Calcium