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POSTIRRADIATION PROTECTION OF X-IRRADIATED MICE WITH OLIVE OIL

Journal Article · · Radiation Research
DOI:https://doi.org/10.2307/3570875· OSTI ID:4178846
Olive oil administered intraperitoneally is both protective and therapeutic to whole-body x-irradiated male Swiss white mice. This beneficial effect is manifested during the bone marrow phase by an increase in survival, a change in the mortality distribution, and a decrease in weight loss. The effect was most pronounced in the MLD group, where almost 90% of the postirradiation oil- treated animals survived. The intraperitoneal administration of lycopene had a questionable effect on irradiated mice. A carefully controlled comparative experiment on irradiation methodology demonstrates the tremendous importance of rigorously controlling physical and biological parameters in radiation protection studies. (auth)
Research Organization:
Univ. of California, Berkeley
Sponsoring Organization:
USDOE
NSA Number:
NSA-14-017756
OSTI ID:
4178846
Journal Information:
Radiation Research, Journal Name: Radiation Research Vol. Vol: 13
Country of Publication:
Country unknown/Code not available
Language:
English

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