ROLE OF THE TIME FACTOR IN DAMAGE DUE TO RADIOACTIVE ISOTOPES

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Biophysics (U.S.S.R.) (English Translation)

OSTI ID:4162173

Moskalev, Yu I ^[1]

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1. Iu.

The blological action of radioactive isotopes depends on the dose, dose rate, and the type of emission. On injury with Sr/sup 90/ and Ce/sup 144/ there exlst doses with a temporary stimulatory effect, others which do not affect the natural life span of the rats, and others which shorten it. On prolonging the time of delivery of the doses of radiation of 8.4 to 27.3 krad, the effectiveness of Ce/sup 141/ as judged by the duration of life of rats is increased; on prolonging the delivery of higher doses, it falls. After damage by Sr/sup 90/ the frequency of onset of osteosarcomas falls, and that of leukemia increases, on lowering the dose rate. As distinct from Sr/sup 90/, with Pu/sup 239/ the frequency of osteosarcoma development increases on reducing the dose rate. As compared with beta emitters the damage induced by alpha emltters is less readily restored and is better summated on prolongation of the action. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-15-001262
• OSTI ID: 4162173
• Journal Information: Biophysics (U.S.S.R.) (English Translation), Journal Name: Biophysics (U.S.S.R.) (English Translation) Vol. Vol: 5
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ALPHA PARTICLES
ALPHA SOURCES
BETA PARTICLES
BIOLOGY AND MEDICINE
BONES
CERIUM 144
EMISSION
LEUKEMIA
LIFETIME
PARTICLE SOURCES
PLUTONIUM 239
RADIATION EFFECTS
RADIOISOTOPES
RATS
STRONTIUM 90
TUMORS