Emesis in monkeys following exposure to ionizing radiation

Journal Article · Sat Feb 01 04:00:00 EST 1975 · Aviat., Space Environ. Med., v. 46, pp. 170-172

OSTI ID:4156851

Middleton, G R; Young, R W

There were 129 male rhesus monkeys (Macaca mulatta) exposed to prompt radiations (neutron/gamma = 0.4 and pulse width = 50 ms) ranging from 700 to 5600 rad (midhead dose). The animals were fasted 18 h preexposure and observed for incidence of vomiting for 2 h postexposure. For doses less than 1000 rads, the number of animals that vomited increased directly with dose. Above 1000 rads, the number of animals that vomited decreased with increasing dose. The total number of vomits per dose group followed a nearly identical pattern to the incidence of emesis. In all dose groups, most of the emetic episodes occurred between 20 and 50 min postirradiation. (auth)

• Research Organization: Armed Forces Radiobiology Research Inst., Bethesda, MD
• NSA Number: NSA-33-007546
• OSTI ID: 4156851
• Journal Information: Aviat., Space Environ. Med., v. 46, pp. 170-172, Journal Name: Aviat., Space Environ. Med., v. 46, pp. 170-172; ISSN ASEMC
• Country of Publication: United States
• Language: English

Related Subjects

*MACACUS-- BIOLOGICAL RADIATION EFFECTS
*VOMITING-- RADIOINDUCTION
560152* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Animals--Vertebrates
DOSE-RESPONSE RELATIONSHIPS
FASTING
GAMMA RADIATION
HEAD
LOCAL IRRADIATION
N48520* --Life Sciences--Radiation Effects on Animals-- Vertebrates
NEUTRONS
PARTIAL BODY IRRADIATION