Effect of continuous-wave and amplitude-modulated 2.45 GHz microwave radiation on the liver and brain aminoacyl-transfer RNA synthetases of in utero exposed mice

Journal Article · Tue Dec 31 04:00:00 EST 1996 · Bioelectromagnetics

DOI:https://doi.org/10.1002/(SICI)1521-186X(1996)17:6<497::AID-BEM10>3.3.CO;2-X· OSTI ID:415623

Kubinyi, G; Thuroczy, G; Bakos, J; Boeloeni, E; Sinay, H; Szabo, L D ^[1]

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1. National Frederic Joliot-Curie Research Inst. for Radiobiology and Radiohygiene, Budapest (Hungary)

Investigations have been carried out concerning the effects of microwave (MW) exposure on the aminoacyl-transfer ribonucleic acid (tRNA) synthetase of the progeny of females that were exposed during their entire period of gestation (19 days). The changes caused by continuous-wave (CW) and amplitude-modulated (AM) MW radiation have been compared. CFLP mice were exposed to MW radiation for 100 min each day in an anechoic room. The MW frequency was 2.45 GHz, and the amplitude modulation had a 50 Hz rectangular waveform (on/off ratio, 50/50%). The average power density exposure was 3 mW/cm{sup 2}, and the whole body specific absorption rate (SAR) was 4.23 {+-} 0.63 W/kg. The weight and mortality of the progeny were followed until postnatal day 24. Aminoacyl-tRNA synthetase enzymes and tRNA from the brains and livers of the offspring (461 exposed, 487 control) were isolated. The aminoacyl-tRNA synthetase activities were determined. The postnatal increase of body weight and organ weight was not influenced by the prenatal MW radiation. The activity of enzyme isolated form the brain showed a significant decrease after CW MW exposure, but the changes were not significant after 50 Hz AM MW exposure. The activity of the enzyme isolated from liver increased under CW and 50 Hz modulated MW.

• OSTI ID: 415623
• Journal Information: Bioelectromagnetics, Journal Name: Bioelectromagnetics Journal Issue: 6 Vol. 17; ISSN 0197-8462; ISSN BLCTDO
• Country of Publication: United States
• Language: English

Related Subjects

56 BIOLOGY AND MEDICINE
APPLIED STUDIES
BIOLOGICAL EFFECTS
BIOLOGICAL MODELS
ENZYME ACTIVITY
GHZ RANGE 01-100
LIGASES
MICROWAVE RADIATION
PRENATAL EXPOSURE
TRANSFER RNA