Multicopper oxidases and oxygenases
- Stanford Univ., CA (United States). Dept. of Chemistry
Copper is an essential trace element in living systems, present in the parts per million concentration range. It is a key cofactor in a diverse array of biological oxidation-reduction reactions. These involve either outer-sphere electron transfer, as in the blue copper proteins and the Cu{sub A} site of cytochrome oxidase and nitrous oxide redutase, or inner-sphere electron transfer in the binding, activation, and reduction of dioxygen, superoxide, nitrite, and nitrous oxide. Copper sites have historically been divided into three classes based on their spectroscopic features, which reflect the geometric and electronic structure of the active site: type 1 (T1) or blue copper, type 2 (T2) or normal copper, and type 3 (T3) or coupled binuclear copper centers. 428 refs.
- Sponsoring Organization:
- National Insts. of Health, Bethesda, MD (United States)
- OSTI ID:
- 415591
- Journal Information:
- Chemical Reviews, Journal Name: Chemical Reviews Journal Issue: 7 Vol. 96; ISSN CHREAY; ISSN 0009-2665
- Country of Publication:
- United States
- Language:
- English
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