INHIBITION AND STIMULATION OF BIOLOGICAL ACTIVITY OF VITAMINS OF GROUP B BY MEANS OF ROENTGEN RADIATION

Journal Article · Wed Jan 01 04:00:00 EST 1958 · Vitamine u. hormone

OSTI ID:4146515

Mucke, D; Morczek, A

With irradiation of thiamine, riboflavin, niacin, biotin, choline, and PABA in crystalline states to a dosage of 5 to 500 r, there was no detection of biological activity as determined by the influence of each of the vitamins on the growth of fungi cultures (respectively). Neurospora crassa ATCC 9185, Y 30539, 4540, Allescheria boydii 1699, Neurospora crassa 34486 and 1633). With approximately the same doses, irradiation of these same vitamins in weak aqueous solutions at a pH of 5.0 to 5.2 led to a significant decrease in their biological activity, irradiation in a nutrient medium solution optimal for each fungus intensified the biological activity of thiamine, choline, and PABA, as was manifested in their fortified stimulation of the growth of the corresponding cultures. Using the same amount of radiation on plain nutrient medium and medium to which the specified vitamins were added, the stimulatory effect was absent.

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-14-023989
• OSTI ID: 4146515
• Journal Information: Vitamine u. hormone, Journal Name: Vitamine u. hormone Vol. Vol: 8, No. 1
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ACIDITY
AGE
BIOLOGY
BIOLOGY AND MEDICINE
CHOLINE
CRYSTALLIZATION
DETECTION
FUNGI
IRRADIATION
LIPIDS
NEUROSPORA
ORGANIC NITROGEN COMPOUNDS
PRECIPITATION
RADIATION CHEMISTRY
RADIATION DOSES
RADIATION EFFECTS
RADIOSENSITIVITY
SOLUTIONS
VARIATIONS
VITAMIN B GROUP
VITAMIN B-1
VITAMIN B-2
VITAMIN H
VITAMIN H-1
VITAMIN PP
VITAMINS
WATER
X RADIATION