THE EFFECTS OF X-IRRADIATION ON THE VITAMIN EXCRETION OF THE RHESUS MONKEY (MACACA MULATTA)

Journal Article · Wed Aug 01 04:00:00 EDT 1956 · J. Nutrition

OSTI ID:4024026

Dutra De Oliveira, J E; Pearson, W N; Misra, K P; Hudson, G W; Darby, W J

Ten monkeys were exposed to three levels (325, 400, 650 r) of x radiation. Anorexin, leucopenia, loss of hair, and at the high levels of irradiation, hemorrhage and diarrhea, followed. Observations on pair-fed non- irradiated controls demonstrated that the decreased urinary excretion of riboflavin, thiamine, and N/sup 1/-methylnicotinamide which followed irradiation was a result of food restriction, not a specific effect of the x-ray injury. No meaningful changes could be found in blood ascorbic acid at the levels of irradiation and intake. Diketogulonic acid excretion was increased in urine after irradiation. A temporary, moderately increased excretion of pteroylglutamic acid and of vitamin B/sub 6/ followed x-irradiation. No prolonged loss of ascorbic acid, riboflavin, thiamine, niacin (N/sup 1/- methylnicotinamide), pyridoxine, or pteroylglutamate occurs which might indicate that x radiation is a conditioning agent in producing a deficiency of these factors. (auth)

• Research Organization: Vanderbilt Univ. School of Medicine, Nashville
• NSA Number: NSA-15-024693
• OSTI ID: 4024026
• Journal Information: J. Nutrition, Journal Name: J. Nutrition Vol. Vol: 59
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD
FOOD
HAIR
HEMORRHAGE
LEUCOCYTES
METABOLISM
MONKEYS
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
URINE
VITAMIN B-6
VITAMIN C
VITAMINS
X RADIATION