Radiosensitization of a human cell line lacking repair replication
Conference
·
OSTI ID:4144991
- ed.
A human cell line has been isolated that is deficient in x-ray-induced repair replication. The slope of the radiation survival curve is greater in the presence of the anthracycline antibiotic, adriamycin. The results suggest that radiosensitization by DNA-binding drugs is more probably related to DNA strand breakage phenomena than to the polymerase step of excision-repair. (auth)
- Research Organization:
- Univ. of California, Los Angeles
- NSA Number:
- NSA-33-012248
- OSTI ID:
- 4144991
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
*ANIMAL CELLS-- RADIOSENSITIVITY
*ANTIBIOTICS-- RADIOSENSITIVITY EFFECTS
*DNA-- BIOLOGICAL REPAIR
560121* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Cells--External Source
BIOLOGICAL RADIATION EFFECTS
MAN
N48210* --Life Sciences--Radiation Effects on Cells-- External Source
SURVIVAL CURVES
X RADIATION
*ANTIBIOTICS-- RADIOSENSITIVITY EFFECTS
*DNA-- BIOLOGICAL REPAIR
560121* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Cells--External Source
BIOLOGICAL RADIATION EFFECTS
MAN
N48210* --Life Sciences--Radiation Effects on Cells-- External Source
SURVIVAL CURVES
X RADIATION