ALTERATIONS IN RADIOSENSITIVITY OF THE HAEMOPOIETIC SYSTEM OF THE MOUSE PRODUCED BY EXTREME HYPOTHERMIA
Journal Article
·
· Intern. J. Radiation Biol.
Mice were given whole-body x irradiation over the dose range 0 to 950 r. Some were irradiated at normal body temperatures and some at body temperatures of l/sup o/C. Others were irradiated at normal body temperatures and then cooled to 1/sup o/C and subsequently resuscitated. The state of the hematopoietic system of such animals, as judged by examination of the bone marrow and by peripheral blood counts at periods of up to five days after irradiation, was studied. lt is shown that hypothermia results in radioprotection of the leucocyte series and their precursors, and it is concluded that this protection is mainly due to concomitant severe hypoxia. (auth)
- Research Organization:
- National Inst. for Medical Research, London
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-001271
- OSTI ID:
- 4144800
- Journal Information:
- Intern. J. Radiation Biol., Journal Name: Intern. J. Radiation Biol. Vol. Vol: 2
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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