URINARY EXCRETION OF RADIUM IN DOGS
Technical Report
·
OSTI ID:4144028
After intravenous injection in adult dogs the average radium clearance is about 1.6 ml per minute with a range (in three dogs) from 1.1 to 2.0 ml. The ultrafilterable fraction of the plasma-radium content is measured as approximately 70%. If this value is compared with similar measurements obtained by other investigators for calcium and strontium it may be inferred that there are no important differences between binding of these three metals insofar as excretory mechanism is concerned. An average value of 95.3% resorption in the tubules was found for radium which may be compared with 97.5% for strontium and 99.4% for calcium established by other workers. These data lead to the conclusion that the differences in urinary excretion in the dog, as expressed in the relationship Ra > Sr > Ca, are brought about principally by corresponding increases in the amount of resorption in the tubules. (auth)
- Research Organization:
- Rochester, N.Y. Univ. Atomic Energy Project
- NSA Number:
- NSA-14-025149
- OSTI ID:
- 4144028
- Report Number(s):
- UR-572
- Country of Publication:
- United States
- Language:
- English
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