Radiological manifestations of radiation-induced injury to the normal upper gastrointestinal tract

Conference · Wed Oct 01 00:00:00 EDT 1975 · Radiology, v. 117, no. 1, pp. 135-140

OSTI ID:4143272

Goldstein, H M; Rogers, L F; Fletcher, G H; Dodd, G D

Radiation-induced injury to the normal esophagus, stomach, and duodenum in patients with advanced cervical carcinoma who received high para-aortic lymph- node irradiation to an average tumor dose of 5,000 rads is discussed. Radiation esophagitis is usually the result of mediastinal irradiation for bronchogenic carcinoma. The most consistent radiological finding is abnormal motility, with esophageal stricture and/or ulceration occurring less frequently. Radiation gastritis is usually present as pyloric ulceration or irregular contractions of the antrum, simulating gastric carcinoma. Postbulbar duodenal mucosal thickening, ulceration, and strictures may occur. Pertinent clinical features, pathogenesis, and pathological correlations are discussed. (auth)

• Research Organization: Univ. of Texas, Houston
• NSA Number: NSA-33-000912
• OSTI ID: 4143272
• Journal Information: Radiology, v. 117, no. 1, pp. 135-140, Conference: 60. scientific assembly and annual meeting of the Radiological Society of North America, Chicago, IL, 1 Dec 1974; Other Information: Orig. Receipt Date: 30-JUN-76
• Country of Publication: United States
• Language: English

Related Subjects

N48510* -Life Sciences-Radiation Effects on Animals-Man
560151* -Biomedical Sciences
Applied Studies-Radiation Effects-Radiation Effects on Animals-Man
*ESOPHAGUS- RADIATION INJURIES
*RADIOTHERAPY- SIDE EFFECTS
*SMALL INTESTINE- RADIATION INJURIES
*STOMACH- RADIATION INJURIES
BIOLOGICAL RADIATION EFFECTS
DELAYED RADIATION EFFECTS
DOSE-RESPONSE RELATIONSHIPS
INFLAMMATION
IRRADIATION
LUNGS
LYMPH NODES
MEDIASTINUM
NEOPLASMS
PATIENTS