Evaluation of technetium-99m DTPA for localization of site of acute upper gastrointestinal bleeding

Journal Article · Sat Nov 01 04:00:00 EST 1986 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198611000-00015· OSTI ID:6857336

Abdel-Dayem, H M; Mahajan, K K; Ericsson, S; Nawaz, K; Owunwanne, A; Kouris, K; Higazy, E; Awdeh, M

Intravenous Tc-99m DTPA was evaluated in 34 patients with active upper gastrointestinal bleeding. Active bleeding was detected in 25 patients: nine in the stomach, 12 in the duodenum, and four from esophageal varices. No active bleeding was seen in nine patients (two gastric ulcers and seven duodenal ulcers). Results were correlated with endoscopic and/or surgical findings. All completely correlated except: 1) one case of esophageal varices in which there was disagreement on the site, 2) three cases of duodenal ulcers that were not bleeding on endoscopy but showed mild oozing on delayed images and 3) one case of gastric ulcer, in which no bleeding was detected in the Tc-99m DTPA study, but was found to be bleeding at surgery 24 hours later. The Tc-99m DTPA study is a reliable method for localization of upper gastrointestinal bleeding with an agreement ratio of 85%. This method also can be used safely for follow-up of patients with intermittent bleeding. It is less invasive than endoscopy, is easily repeatable, and has the same accuracy.

• Research Organization: Kuwait Univ.
• OSTI ID: 6857336
• Journal Information: Clin. Nucl. Med.; (United States), Journal Name: Clin. Nucl. Med.; (United States) Vol. 11; ISSN CNMED
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL LOCALIZATION
CARBOXYLIC ACIDS
CHELATING AGENTS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DRUGS
DTPA
EVALUATION
GASTROINTESTINAL TRACT
HEMORRHAGE
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
PATHOLOGICAL CHANGES
PATIENTS
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
ULCERS
YEARS LIVING RADIOISOTOPES