BONE MARROW AND ORGAN CHANGES IN IRRADIATED DORMICE

Journal Article · Sun May 01 04:00:00 EDT 1960 · Strahlentherapie (West Germany)

OSTI ID:4140626

Heckmann, U; Kunkel, H A

Hibernating loirs (glis glis) survive a whole body irradiation with lethal doses for several weeks without external visible damage, if they stay in hibernation. At the end of the hibernation the radiation damage becomes visible and the animals die as if they were irradiated at the time of their waking-up. A cysteine administration at the time of the waking-up (3 weeks following the irradiation) has a significant protective effect. Numerous histological studies on bone marrow, spleen, liver, kidney, adrenals and testes showed that the damage of the cells becomes visible already during the hibernation, but less marked and more protracted than in awake animals. An effect on these radiation induced changes by administration of cysteine following the irradiation could be observed on the plasma and reticulum cells and on the histological structures of the liver. (auth)

• Research Organization: Universitats-Frauneklinik Hamburg-Eppendorf, Ger.
• NSA Number: NSA-14-014712
• OSTI ID: 4140626
• Journal Information: Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 112; ISSN STRAA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

ADRENAL GLANDS
ANIMAL CELLS
ANIMALS
BIOLOGY AND MEDICINE
BLOOD PLASMA
BODY
BONE MARROW
CYSTEINE
GONADS
HIBERNATION
KIDNEYS
LETHAL DOSE
LIVER
METABOLISM
RADIATION EFFECTS
RADIATION INJURIES
RADIATION PROTECTION
SPLEEN
TISSUES