SURVIVAL OF CALVES TREATED WITH AUTOLOGOUS BONE MARROW AFTER EXPOSURE TO LETHAL DOSE OF WHOLE-BODY IRRADIATION

Journal Article · Mon Oct 31 23:00:00 EST 1960 · Proc. Soc. Exptl. Biol. Med.

DOI:https://doi.org/10.3181/00379727-105-26096· OSTI ID:4139039

Mizuno, N S; Perman, V; Joel, D D; Bates, F W; Sautter, J H; Schultze, M O

lntravenous injection of homologous bone marrow or of a mixture of fetal liver, spleen, and thymus after exposure to a lethal dose of whole-body radiation failed to protect calves against death from bone marrow damage. Nine of 15 calves treated with autologous bone marrow recovered after a severe hematologic crisis; 8 of these developed normally, showed no apparent signs of late radiation damage, and had regular estrous cycles and 7 are now pregnant. (auth)

• Research Organization: Univ. of Minnesota, St. Paul
• Sponsoring Organization: USDOE
• NSA Number: NSA-15-003898
• OSTI ID: 4139039
• Journal Information: Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 105
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMALS
BIOLOGY AND MEDICINE
BLOOD
BLOOD CELLS
BONE MARROW
FETUSES
GAMMA RADIATION
GLANDS
LETHAL DOSE
LIFETIME
LIVER
RADIATION INJURIES
RADIATION PROTECTION
RECOVERY
SPLEEN
THYMUS