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THE CHANGES OF CONDITIONED DEFENSIVE REFLEXES IN DOGS IN RADIATION SICKNESS

Journal Article · · Ezhegodnik Inst. Eksptl'. Med. Akad. Med. Nauk S.S.S.R.
OSTI ID:4136335
Two dogs received general roentgen irradiation in a dose of 460 r with a power of 17 r/min. To a third dog a solution of P/sup 32/ in a dose which corresponded to about 200 r was introduced intravenously. In all dogs, defensiveconditioned reflexes (CR; raising of paw) were produced. The latent period, the number of raisings of the paw in response to the conditioned stimulus, the number of respiratory movements during its duration, and the number of intersignal reactions were registered. The clinical picture of the disease was determined according to morphological composition of blood and weight of the animals. In both variations of irradiation, phase changes of the values of CR were observed. The periods of relative decrease of the values of CR coincided with the critical periods of the course of radiation sickness. The periods of fall of the number of leucocytes in the blood either preceded the periods of relative decrease of values of CR, or coincided with them. Normal interrelations between the values of CR in their decrease were preserved, which apparently indicates an increase of processes of inhibition at the expense of induction influences from other regions of the nervous system.
Research Organization:
Inst. of Experimental Medicine, USSR
NSA Number:
NSA-14-025380
OSTI ID:
4136335
Journal Information:
Ezhegodnik Inst. Eksptl'. Med. Akad. Med. Nauk S.S.S.R., Journal Name: Ezhegodnik Inst. Eksptl'. Med. Akad. Med. Nauk S.S.S.R. Vol. Vol: 2, (M)
Country of Publication:
Country unknown/Code not available
Language:
English

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