THE CHANGE IN VASOMOTOR AND SECRETORY CONDITIONED AND UNCONDITIONED REFLEXES DURING ACUTE RADIATION SICKNESS
>Regulation of the vascular tonus as a function of the general condition of CNS during acute radiation sickness was studied. The reflex reactions were studied by recording the plethysmographical changes in the vascular lumen of the marginal vein of the ear and by measuring the saliva secretion from the parotid gland in dogs. An unconditioned stimulus in the form of a 0.25% HCl solution sprayed into the mouth cavity, produced vascular constriction and saliva secretion. Four female dogs were subjected to simultaneous bilateral irradiation. The dose was 500 r at 6.3 r/min. The conditioned and unconditioned vascular and secretory reflexes were altered phasically and in a similar manner with the progress of radiation sickness. CNS was affected on both cortical and subcortical levels, especially in severe cases. At the terminal stage of the sickness a diffuse suppression of CNS activity was observed. The pathogenesis of the general vascular disorders in radiation sickness originated to a great extent from the functional disorders of the higher levels of CNS. (P.C.H.)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-17-012177
- OSTI ID:
- 4762293
- Journal Information:
- Zh. Vysshei Nervnoi Deyatel'nosti, im. I.P. Pavlova, Journal Name: Zh. Vysshei Nervnoi Deyatel'nosti, im. I.P. Pavlova Vol. Vol: 12
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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