RADIOGRAPHIC APPEARANCES OF BONE LESIONS IN RATS EXPOSED TO LOCAL EXTERNAL IRRADIATION FROM GAMMA RAYS
Journal Article
·
· Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn.
The development of bone lesions was followed radiographically after a single dose of 3000 r gamma rays from an Ir/sup 192 source applied to both knees of 136 rats. Stunted/ growth of bone was the earliest detectable change. At 6 months, zones of osteolysis and osteosclerosis were frequent. Transverse bars of bone, pathologic fractures, and destruction of bone were also seen; some lesions persisted, others healed. Epiphyseal cartilages were thickened in 100% and doubled in 25% of irradiated rats. Osteosarcomata developed in 34 out of 116 rats surviving more than 250 days. (auth)
- Research Organization:
- Cambridge Univ., Eng.; Northwestern Univ., Chicago; Argonne National Lab., Ill.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-002453
- OSTI ID:
- 4132876
- Journal Information:
- Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn., Journal Name: Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn. Vol. Vol: 54; ISSN ACRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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