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RADIOGRAPHIC CHANGES FOLLOWING THE ADMINISTRATION OF BONE-SEEKING RADIONUCLIDES

Journal Article · · Brit. J. Radiol.

During investigations on the carcinogenic effects of alpha and BETA - emitting radionuclides, serial radiographs of rats injected with single and repeated doses of P/sup 32/, Pu/sup 239/ or Am/sup 241/ were studied to record the development of radioinduced changes. Among the lesions observed were failure of longitudinal bone growth, abnormal bone moulding, pathological fractures, and the production of sclerosing, lytic, and mixed forms of osteosarcoma. The induction of bone tumors could be identified early and the development followed closely; radiographic changes are described. (auth)

Research Organization:
Inst. of Cancer Research, Belmont, Surrey, Eng.
Sponsoring Organization:
USDOE
NSA Number:
NSA-18-009848
OSTI ID:
4085946
Journal Information:
Brit. J. Radiol., Journal Name: Brit. J. Radiol. Vol. Vol: 37
Country of Publication:
Country unknown/Code not available
Language:
English

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