Nuclear-fueled circulatory support systems. XII. Current status

Journal Article · Tue Jan 01 04:00:00 EST 1974 · Trans., Am. Soc. Artif. Intern. Organs, v. 20, pp. 737-746

OSTI ID:4132403

Hughes, D A; Faeser, R J; Daly, B D.T.

Our laboratories have been engaged in development and in vivo testing of nuclear-fueled circulatory support systems. These efforts have focused on 4 major areas: (1) evaluations of the biologic effects of chronic intracorporeal heat and radiation; (2) the development of efficient and reliable energy converters (engines); (3) evaluations of the biocompatibility of the various system components, and (4) investigations of the hemodynamic effectiveness of the system in vivo. Previous in vivo experiments have been reported. Three systems are currently under investigation; each has undergone a number of modifications to improve overall thermal-mechanical efficiencies or to decrease physiologic alterations resulting from system size, intracorporeal heat and interactions between the prostheses and experimental animals. The purpose of this paper is to characterize the current systems and describe recent in vivo experiments. (auth)

• Research Organization: Cardiovascular Surgical Research Labs., Houston, TX
• NSA Number: NSA-33-009417
• OSTI ID: 4132403
• Journal Information: Trans., Am. Soc. Artif. Intern. Organs, v. 20, pp. 737-746, Journal Name: Trans., Am. Soc. Artif. Intern. Organs, v. 20, pp. 737-746; ISSN TAIOA
• Country of Publication: United States
• Language: English

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