LABILIZATION OF DEOXYRIBONUCLEIC ACID IN THYMUS NUCLEOPROTEIN AFTER WHOLE- BODY IRRADIATION
Rats were irradiated with 200 kev x rays in order to study the firmness of the binding between the deoxyribonucleic acid and its protein. A maximum yield of deoxyribonucleic acid was obtained from the thymus with 2% trichloroacetic acid. The yields were much greater after whole-body irradiation than that from a normal thymus. The increase in yield was dependent on the dose. The observed effect can be explained either by a break or weakening of some bivalent metal linkage between deoxyribonucleic acid and protein or by a higher concentration of deoxypolynucleotides in the thymus. (M.C.G.)
- Research Organization:
- Heiligenberg-Institut, Baden, Ger.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-025338
- OSTI ID:
- 4131600
- Journal Information:
- Nature, Journal Name: Nature Vol. Vol: 187
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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