Data on the action spectrum for ultraviolet carcinogenesis

Journal Article · Sat Nov 01 04:00:00 EST 1975 · J. Natl. Cancer Inst., v. 55, no. 5, pp. 1119-1122

OSTI ID:4130605

Freeman, R G

When 300, 310, or 320 nm monochromatic energy was given to albino mice in amounts proportional to its erythemal effectiveness, skin tumors developed on the exposed ears of the mice at approximately the same time and the same rate in all three groups. Thus the long wavelength limit of the carcinogenesis action spectrum paralleled that of the erythema action spectrum. No tumors were found in mice exposed to a 290-nm uv wavelength nor in those exposed to low dosages at 310 nm. All tumors observed in the group exposed to 300 nm were squamous cell carcinomas; three sarcomas and five squamous cell carcinomas were seen with the more penetrating doses of a 310-nm uv wavelength. (auth)

• Research Organization: Baylor Coll. of Medicine, Houston, TX
• NSA Number: NSA-33-009555
• OSTI ID: 4130605
• Journal Information: J. Natl. Cancer Inst., v. 55, no. 5, pp. 1119-1122, Journal Name: J. Natl. Cancer Inst., v. 55, no. 5, pp. 1119-1122; ISSN JNCIA
• Country of Publication: United States
• Language: English

Related Subjects

*NEOPLASMS-- RADIOINDUCTION
*SKIN-- BIOLOGICAL RADIATION EFFECTS
*ULTRAVIOLET RADIATION-- CARCINOGENESIS
560152* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Animals--Vertebrates
IRRADIATION
MICE
N48520* --Life Sciences--Radiation Effects on Animals-- Vertebrates