DIFFERENCES IN THE DISTRIBUTION OF ZIRCONIUM-95 AND NIOBIUM-95 IN THE RAT

Journal Article · Sat Jan 25 04:00:00 EST 1964 · Nature

DOI:https://doi.org/10.1038/201410a0· OSTI ID:4128844

Sastry, B V.R.; Owens, L K; Ball, C O.T.

Physical decay patterns of Zr/sup 95/-Nb/sup 95/ were determined in rat tissues to show whether some tissues prefer Zr/sup 95/ while others concentrate Nb/sup 95/ in four days after interperitoneal administration of Zr/sup 95/- Nb/ sup 95/ in transient equilibrium. Twelve male Spragre-Dawley rats were injected with carrier-free Zr/sup 95/-- Nb/sup 95/ as oxalates in normal saline. After four days the animals were sacrificed by decapitation. Bones, muscles, liver, kidneys, gonads, heart, lungs, and spleen from each animal were dissected. Physical decay patterns of the nuclide pair were determined by standard gamma - scintillation spectrometric methods. Bones accumulated the parent isotope preferentially, whereas blood retained the niobium-95 daughter. Therefore, results show that although zirconium and niobium are in the second transitional series and resemble each other in many of their physico-chemical properties, rat tissue membranes show differential transpont between Zr/sup 95/ and Nb/sup 95/. (H.M.G.)

• Research Organization: Vanderbilt Univ., Nashville
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-011604
• OSTI ID: 4128844
• Journal Information: Nature, Journal Name: Nature Vol. Vol: 201
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD
BONES
DECAY
DISTRIBUTION
GAMMA SPECTROMETERS
GONADS
HEART
KIDNEYS
LABELLED COMPOUNDS
LIVER
LUNGS
MEMBRANES
MUSCLES
NIOBIUM 95
OXALATES
RATS
SPLEEN
TISSUES
VARIATIONS
ZIRCONIUM 95