CARCINOMA OF THE MAXILLARY SINUS FOLLOWING THOROTRAST INSTILLATION: A FURTHER REPORT
Since an earlier report from this hospital in 1960 of three cases of carcinoma of the maxillary sinus following Thorotrast instillation, three additional cases of maxillary sinus carcinoma following Thorotrast instillation are reported. In all three cases, radioactivity of the specimen was significant and found to be the activity of Th and its decay products. The first case gave a history of roentgenographic studies of nasal sinuses with Thorotrast about 20 years prior to admission. The second patient was a 49-yr-old man with a history of having had an injection into the right maxillary sinus about 20 years before admission for allergy studies. The third patient was a 46-yr-old man with a history of allergy and who had had radiopaque material injected into his sinus cavity for roentgenographic studies about 15 years prior to admission. These cases add to the mounting number which implicate the persistent radioactivity of Th as a carcinogenic hazard. The latent period between injection and discovery of tumor in these three cases varied from 15 to 20 years. The carcinogenic effect of the radioactivity of Th and its decay products is discussed. (BBB)
- Research Organization:
- Presbyterian Hospital, New York
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-18-011660
- OSTI ID:
- 4128065
- Journal Information:
- American Journal of Surgery (U.S.), Journal Name: American Journal of Surgery (U.S.) Vol. Vol: 106; ISSN AJSUA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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