Fate of uv-induced pyrimidine dimers in the nuclear and mitochondrial DNAs of Saccharomyces cerevisiae on various postirradiation treatments and its influence on survival and cytoplasmic 'petite' induction

Conference · Wed Jan 01 00:00:00 EST 1975

OSTI ID:4125891

Waters, R; Moustacchi, E; Hanawalt, P C ^[1]

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1. ed.

The photoreactivability of uv-induced pyrimidine dimers in the nuclear and mitochondrial DNAs of Saccharomyces cerevisiae has been investigated in conjunction with the fate of these photoproducts following postirradiation dark incubation in saline and nutrient media. In all instances, survival and ''petite'' induction were measured. An attempt has been made to relate these results to present ideas on the repair of uv damages in DNA. (auth)

• Research Organization: Inst. du Radium-Biologie, Orsay, France
• NSA Number: NSA-33-012302
• OSTI ID: 4125891
• Resource Relation: Conference: DNA repair processes conference, Squaw Valley, California, USA, Feb 1974; Other Information: See CONF-740231--PB. Orig. Receipt Date: 30-JUN-76; Related Information: Molecular mechanisms for repair of DNA. Part B
• Country of Publication: United States
• Language: English

Related Subjects

N48310* -Life Sciences-Radiation Effects on Microorganisms- -Basic Studies
N48110 -Life Sciences-Radiation Effects on Biochemicals-In-Vitro
560131* -Biomedical Sciences
Applied Studies-Radiation Effects-Radiation Effects on Microorganisms-Basic Studies
*DIMERS- BIOCHEMICAL REACTION KINETICS
*DNA- BIOLOGICAL REPAIR
*PYRIMIDINES- BIOCHEMICAL REACTION KINETICS
*SACCHAROMYCES CEREVISIAE- BIOLOGICAL RADIATION EFFECTS
CELL NUCLEI
MITOCHONDRIA
PHOTOREACTIVATION
ULTRAVIOLET RADIATION