Excretion rate and retention of plutonium 10,000 days after acquisition

Conference · Wed Jan 01 04:00:00 EST 1975

OSTI ID:4124623

Rundo, J; Starzyk, P M; Sedlet, J; Larsen, R P; Oldham, R D; Robinson, J J

Three persons who had been injected with known amounts of plutonium in 1945 to 1947, were hospitalized on a metabolic ward in 1973. All excreta were collected for at least eight days and the samples were analyzed for plutonium. For the two subjects who had been injected intravenously with tetravalent $sup 239$Pu as the citrate, the urinary excretion rates were 7.6 and 4.7 pCi/day at approximately 10$sup 4$ days after injection; these rates corresponded to 2.52 x 10$sup -3$ percent of the injected doses per day respectively. The fecal excretion rates were about 40 percent of the urinary rates. The third subject received an intramuscular injection of hexavalent $sup 238$Pu as the nitrate, in the left leg, which was amputated four days later. Almost 50 percent of the amount injected was found at the injection site and the urinary excretion rate about 9500 days later was 0.06 pCi/day, corresponding to not less than 1.2 x 10$sup -4$ percent of the initial systemic burden. The excretion rate and retention of $sup 239$Pu up to 10,000 days post-injection were calculated. (CH)

• Research Organization: Argonne National Lab., Ill. (USA)
• DOE Contract Number: W-31109-ENG-38
• NSA Number: NSA-33-012447
• OSTI ID: 4124623
• Report Number(s): CONF-751205--5; SR--6/23
• Country of Publication: United States
• Language: English

Related Subjects

*MAN-- RADIONUCLIDE KINETICS
*PLUTONIUM 238-- RETENTION FUNCTIONS
*PLUTONIUM 239-- RETENTION FUNCTIONS
560171* --Biomedical Sciences
Applied Studies--Radiation Effects--Nuclide Kinetics & Toxicology--Man
CITRATES
EXCRETION
FECES
INTRAMUSCULAR INJECTION
INTRAVENOUS INJECTION
N48710* --Life Sciences--Nuclide Kinetics & Toxicology--Man
NITRATES
TIME DEPENDENCE
URINE