Plutonium in mammals: influence of plutonium chemistry, route of administration, and physiological status of the animal on initial distribution, and long-term metabolism

Conference · Wed Oct 01 04:00:00 EDT 1975 · Health Phys., v. 29, no. 4, pp. 495-510

OSTI ID:4124462

Durbin, P W

Current concepts of Pu metabolism are reviewed. Metabolic models of the Pu intake by human populations of mixed age are based on certain over-simplified assumptions which are here considered and the factors that influence the absorption and distribution of Pu in animals and the long-term fate of Pu are discussed. The factors examined include; chemical properties of biological importance, gastrointestinal absorption, absorption from parenteral sites, absorption from the lung, body and tissue distribution of soluble plutonium, plutonium deposition and skeletal maturity, tissue distribution of particulate plutonium, long-term fate of particulate plutonium and of initially soluble plutonium. (UK)

• Research Organization: Univ. of California, Berkeley
• NSA Number: NSA-33-009631
• OSTI ID: 4124462
• Conference Information: Journal Name: Health Phys., v. 29, no. 4, pp. 495-510
• Country of Publication: United Kingdom
• Language: English

Related Subjects

*MAMMALS-- RADIONUCLIDE KINETICS
*PLUTONIUM-- METABOLISM
560172* --Biomedical Sciences
Applied Studies--Radiation Effects--Nuclide Kinetics & Toxicology--Animals
AGE DEPENDENCE
CHEMICAL COMPOSITION
HUMAN POPULATIONS
INTAKE
N48720* --Life Sciences--Nuclide Kinetics & Toxicology-- Animals
REVIEWS
SKELETON
TISSUE DISTRIBUTION
UPTAKE