Excision of pyrimidine dimers in toluene-treated Escherichia coli

Journal Article · Thu Jan 01 04:00:00 EST 1976 · J. Bacteriol., v. 125, no. 1, pp. 220-224

OSTI ID:4120647

Deutsch, W A; Dorson, J W; Moses, R E

Toluene-treated cells were used for examining excision of pyrimidine dimers in Escherichia coli strains W3110, DM845 (uvrA$sup -$), P3478 (polA$sup - $), and KS5064 (polA/sub ex1/). Excision occurring in toluene-treated cells is rapid adenosine 5'-triphosphate dependent, and requires the uvrA gene function. In strains lacking either the polymerizing or 5' $Yields$ 3' exonucleolytic activity of deoxyribonucleic acid polymerase I, excision does occur. However, both in vivo and in vitro, the excision in such strains is initially slower than wild type. (auth)

• Research Organization: Baylor Coll. of Medicine, Houston, TX
• NSA Number: NSA-33-017343
• OSTI ID: 4120647
• Journal Information: J. Bacteriol., v. 125, no. 1, pp. 220-224, Journal Name: J. Bacteriol., v. 125, no. 1, pp. 220-224; ISSN JOBAA
• Country of Publication: United States
• Language: English

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