EFFECT OF NARCOSIS AND OF AN ABDOMINAL OPERATION ON THE COURSE OF RADIATION SICKNESS

Journal Article · Tue Jan 01 04:00:00 EST 1957 · Trudy Vsesoyuz. Konf. Med. Radiol.

OSTI ID:4118168

Tikhonin, I Ya; Kas'yanov, I S; Vaganova, N T

Groups of rabbits and dogs were irradiated at 600 and 500 r, respectively. anesthetized with morphine-ether or by a nerve block with Novocain, and operated upon for stomach resection with an infusion of penicillin to prevent iinfection. One control group was anesthetized and operated upon, but wss not irrsdiated. Another control group was irradiated and anesthetized. but was not operated upon. The use of a morphine-ether anesthetic during operation resulted in a cessation of respiration and enlargement of the right side of the heart (7 out of 11 animals died during the operation). No complications could be observed with the use of a Novocain block as an anesthetic. The most favorable period for operative intervention was the latent period (one to two days after irradiation). Operations per formed at the height of the radiation sickness (7 to 14 days after irradiation) were complicated by a failure of the incision to close, necrosis at the site of the incision, and an increased tendency to hemorrhage during the operation. Leukopenia, decreased hemoglobin, a decrease in the albumin to globulin ratio. and a decrease in the number of erythrocytes were observed in all animals during the postoperative period. (TTT)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-15-002550
• OSTI ID: 4118168
• Journal Information: Trudy Vsesoyuz. Konf. Med. Radiol., Journal Name: Trudy Vsesoyuz. Konf. Med. Radiol.
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ALBUMINS
ANESTHESIA
ANIMALS
ANTIBIOTICS
BIOLOGY AND MEDICINE
BLOOD SERUM
ERYTHROCYTES
ETHERS
HEART
HEMOGLOBIN
HEMORRHAGE
LEUCOCYTES
LIFETIME
LUNGS
PROTEINS
RABBITS
RADIATION SICKNESS
STOMACH
SURGERY