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A LONG-TERM FEEDING STUDY OF IRRADIATED FOODS USING RATS AS EXPERIMENTAL ANIMALS

Journal Article · · Federation Proc.
OSTI ID:4113036
S>In one series of tests, four generations of rats received an irradiated synthetic diet. Growth and reproduction performance of the animals receiving the irradiated diet were essentially equal to those of animals receiving the nonirradiated or control diet. In a second series of tests, four generations of rats received nine different combinations of control and irradiated green beans and boned chicken. Each food was irradiated at dose levels of zero, 2.79, and 5.58 megarads. No significant differences in gain in weight at 12 weeks occurred in the parent, F/sub 1/, and F/sub 2/ generations for any combination of the irradiated and control foods. Likewise, irradiation of the food did not effect the hemato logic or histopathologic picture or the weights of heart, lungs, liver, spleen, kidneys, or testes. A few blind young were weaned from mothers receiving both the irradiated and control foods. Blindness occurred also in groups of young from mothers receiving synthetic diets which had not been irradiated. In some cases, the incidence of blindness was higher in the young from these diets than it was from the irradiated. The over- all data show that the blindness which occurred was not due to the irradiated food. (auth)
Research Organization:
Texas Agricultural Experimental Station, College Station; and Univ. of Texas Medical Branch, Galveston
NSA Number:
NSA-15-005290
OSTI ID:
4113036
Journal Information:
Federation Proc., Journal Name: Federation Proc. Vol. Vol: 19
Country of Publication:
Country unknown/Code not available
Language:
English