MEDICAL DIVISION RESEARCH REPORT FOR 1963
Patients with chronic lymphatic or chronic myelocytic leukemia were exposed to whole-body single doses of 50 r gamma radiation, and patients with lymphosarcoma were exposed to whole-body single doses of 100 r gamma radiation. Clinical response and hematological data are reported. An evaluation was made of 95 patients with ovarian carcinoma treated with intraperitoneal radioisotope therapy. Preliminary data are presented from studies of amino acid metabolism in mouse radiation chimeras; viability studies on frozen human bone marrow; diffusion chamber cultivation of human lymph node tissue; antibody synthesis in cultured mouse tissues; the effects of whole-body gamma irradiation on immune reactions and chimerism in the primate Tamarinus nigricallis; factors affecting the selective localization of Ce/sup 144/ ceramic microspores or chelates and colloidal P/sup 32/- or Cr/sup 51/-labeled chromic phosphate after lymphatic injection in dogs; the induction of fatty liver in rats by intravenously injected chelates of Ce, Nd, or Sm; the distribution of Ba/sup 137/ in rats; the use of I/ sup 131/-hippuran in renal function tests; the effectiveness of intermittent corticosteroid therapy in malignant lymphatic diseases; and the development of a rapid method for the detection of vitamin B/sub 12/ distribution using an arm counter and Co/sup 60/ as a tracer. Design modifications are reported in radiation detection instruments for use as whole-body and single arm counters. (C.H.)
- Research Organization:
- Oak Ridge Inst. of Nuclear Studies, Inc., Tenn. Page(s): 109
- NSA Number:
- NSA-18-013390
- OSTI ID:
- 4094323
- Report Number(s):
- ORINS-43
- Country of Publication:
- United States
- Language:
- English
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