ARTERIAL BLOOD PRESSURE IN THE COURSE OF RADIATION SICKNESS IN DOGS
Blood pressure was measured in dogs before and after irradiation using a direct method. In the first group irradiated with a dose of 500 r a moderate, gradual increase in systolic, diastolic, and mean arterial pressure, with a significant increase in the systolic pressure, was observed 42 days after irradiation. In animals irradiated with 600 r, a slight decrease in the pressure values was observed which was statistically significant eight days after irradiation. Similar changes occurred also in the third group irradiated with 800 r, the decrease being not statistically significant. It is concluded that in radiation sickness induced by whole-body irradiation up to a lethal dose there was no marked, lasting hypotension which might influence the course of radiation sickness. It is possible that these measurements did not detect temporary hypotension as previously described in the first hours following irradiation. It is suggested that it is important to measure the blood pressure without anesthesia which may, especially in irradiated animals, considerably influence blood pressure toward hypotension. (BBB)
- Research Organization:
- Charles Univ., Koniggratz, Czechoslovakia
- NSA Number:
- NSA-18-013542
- OSTI ID:
- 4088971
- Journal Information:
- Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradei Kralove, Journal Name: Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradei Kralove Vol. Vol: 6
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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