INFLUENCE OF X-RAY IRRADIATION ON THE FORMATION OF OXIDATION PRODUCTS OF LIPIDS IN LIVER MITOCHONDRIA OF RATS

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradci Kralove

OSTI ID:4085486

Lejsek, K

The ability of liver mitochondria in rats (isolated in saccharose medium) to create substances reacting with thiobarbituric acid during the incubation at 37 and 4 deg C (in medium 0.15 M NaCl) was not significantly influenced by the irradiation of rats in vivo with a dose of 600 r the first, third, and sixth day before removal of the organs. During irradiation of isolated mitochondria in vitro by a dose of 10000 r, the amount of oxidation products of lipids measured by the thiobarbituric acid test immediately after irradiation and after 15 minute's incubation at 37 deg C increased statistically significantly. After 30, 60, 120, 180, and 240 minute's incubation the average amount of thiobarbituric acid chromogens was higher than that in control suspensions, the increase, however, was not statistically significant. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-18-009892
• OSTI ID: 4085486
• Journal Information: Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradci Kralove, Journal Name: Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradci Kralove Vol. Vol: 6
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANIMAL CELLS
BARBITURIC ACID
BIOLOGY AND MEDICINE
DRUGS
LIVER
MEASURED VALUES
METABOLISM
MITOCHONDRIA
ORGANIC ACIDS
ORGANIC SULFUR COMPOUNDS
OXIDATION
RADIATION DOSES
RADIATION EFFECTS
RATS
SACCHAROSE
SOLUTIONS
SUGARS
TEMPERATURE
TISSUES
VARIATIONS
X RADIATION