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Title: ACTION OF TRITIATED TETANUS TOXIN AND TOXOID UPTON THE NERVOUS SYSTEM AND UPON THE ANTIBOYD FORMING MECHANISM. Period covered: April 1, 1959-March 31, 1961

Abstract

>Progress is reported in studies on the action of tritiated tetanus toxin and toxoid upon the nervous system and upon the antibody forming mechanisms in mice. Procedures are described for the preparation of purified tritiated tetanus toxin. The tritiated toxin was injected into mice immunized to tetanus toxoid. Distinct differences were noted in the cellular reaction to the tritiated antigen in immunized and control animals. The data suggest that antibody-producing cells contain antigen at the time antibody is being produced. A quantitative procedure was developed for determining the number of cells responding during an inflammation. Procedures were developed for the automatic processing of radioautograms. ( C.H.)

Authors:
Publication Date:
Research Org.:
New York. State Univ., Albany. Research Foundation
OSTI Identifier:
4082660
Report Number(s):
TID-11330
NSA Number:
NSA-15-005878
DOE Contract Number:  
AT(30-1)-2414
Resource Type:
Technical Report
Resource Relation:
Other Information: Orig. Receipt Date: 31-DEC-61
Country of Publication:
United States
Language:
English
Subject:
BIOLOGY AND MEDICINE; ANIMAL CELLS; ANTIBODIES; ANTIGENS; DISEASES; IMMUNITY; MICE; NERVOUS SYSTEM; RADIOAUTOGRAPHY; TOXICITY; TRACER TECHNIQUES; TRITIUM

Citation Formats

Speirs, R.S.. ACTION OF TRITIATED TETANUS TOXIN AND TOXOID UPTON THE NERVOUS SYSTEM AND UPON THE ANTIBOYD FORMING MECHANISM. Period covered: April 1, 1959-March 31, 1961. United States: N. p., 1961. Web.
Speirs, R.S.. ACTION OF TRITIATED TETANUS TOXIN AND TOXOID UPTON THE NERVOUS SYSTEM AND UPON THE ANTIBOYD FORMING MECHANISM. Period covered: April 1, 1959-March 31, 1961. United States.
Speirs, R.S.. Tue . "ACTION OF TRITIATED TETANUS TOXIN AND TOXOID UPTON THE NERVOUS SYSTEM AND UPON THE ANTIBOYD FORMING MECHANISM. Period covered: April 1, 1959-March 31, 1961". United States.
@article{osti_4082660,
title = {ACTION OF TRITIATED TETANUS TOXIN AND TOXOID UPTON THE NERVOUS SYSTEM AND UPON THE ANTIBOYD FORMING MECHANISM. Period covered: April 1, 1959-March 31, 1961},
author = {Speirs, R.S.},
abstractNote = {>Progress is reported in studies on the action of tritiated tetanus toxin and toxoid upon the nervous system and upon the antibody forming mechanisms in mice. Procedures are described for the preparation of purified tritiated tetanus toxin. The tritiated toxin was injected into mice immunized to tetanus toxoid. Distinct differences were noted in the cellular reaction to the tritiated antigen in immunized and control animals. The data suggest that antibody-producing cells contain antigen at the time antibody is being produced. A quantitative procedure was developed for determining the number of cells responding during an inflammation. Procedures were developed for the automatic processing of radioautograms. ( C.H.)},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1961},
month = {10}
}

Technical Report:
Other availability
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