ACTION OF TRITIATED TETANUS TOXIN AND TOXOID UPTON THE NERVOUS SYSTEM AND UPON THE ANTIBOYD FORMING MECHANISM. Period covered: April 1, 1959-March 31, 1961
>Progress is reported in studies on the action of tritiated tetanus toxin and toxoid upon the nervous system and upon the antibody forming mechanisms in mice. Procedures are described for the preparation of purified tritiated tetanus toxin. The tritiated toxin was injected into mice immunized to tetanus toxoid. Distinct differences were noted in the cellular reaction to the tritiated antigen in immunized and control animals. The data suggest that antibody-producing cells contain antigen at the time antibody is being produced. A quantitative procedure was developed for determining the number of cells responding during an inflammation. Procedures were developed for the automatic processing of radioautograms. ( C.H.)
- Research Organization:
- New York. State Univ., Albany. Research Foundation
- DOE Contract Number:
- AT(30-1)-2414
- NSA Number:
- NSA-15-005878
- OSTI ID:
- 4082660
- Report Number(s):
- TID-11330
- Resource Relation:
- Other Information: Orig. Receipt Date: 31-DEC-61
- Country of Publication:
- United States
- Language:
- English
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